Search 105,200+ Vacation Rentals

Edisto Island 4+ bedroom Beach Rentals, Vacation Rentals & More - 188 Rentals Available.

Payment Protection
To book this vacation rental you need to pay through the Vacation Home Rentals website. We can’t protect your payment if you don’t pay through us. Learn more

188 Vacation rentals

Filters applied: 4 Bedrooms

1 / 19

Edisto Island House

  • 4
  • 13
  • Min stay varies
  • Ask about children
  • Air conditioning

from $111 / night

1 / 14

Edisto Island House

  • 4
  • 10
  • Min stay varies
  • Ask about children
  • Air conditioning
  • Pet friendly

from $91 / night

(2)

1 / 22

Edisto Island House

  • 4
  • 10
  • 3 nights min
  • Swimming pool
  • Child friendly
  • Air conditioning

$183

Excellent (2 reviews)

Inquire

from $183 / night

1 / 19

Edisto Island House

  • 4
  • 13
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Pet friendly

from $215 / night

1 / 31

Edisto Island House

  • 4
  • 14
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Ask about pets

from $116 / night

1 / 24

Edisto Island House

  • 4
  • 12
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Ask about pets

from $357 / night

(2)

1 / 28

Edisto Island House

  • 4
  • 8
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Ask about pets

$132

Average (2 reviews)

Inquire

from $132 / night

(1)

1 / 43

Edisto Island House

  • 4
  • 13
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Ask about pets

$236

Very Good (1 reviews)

Inquire

from $236 / night

1 / 41

Edisto Island House

  • 4
  • 12
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Pet friendly

from $149 / night

1 / 22

Edisto Island House

  • 4
  • 12
  • 3 nights min
  • Swimming pool
  • Child friendly
  • Air conditioning

from $416 / night

1 / 20

Edisto Island House

  • 4
  • 8
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Pet friendly

from $159 / night

1 / 19

Edisto Island House

  • 4
  • 12
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Ask about pets

from $292 / night

1 / 31

Edisto Island House

  • 4
  • 14
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Ask about pets

from $283 / night

1 / 22

Edisto Island House

  • 4
  • 8
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Pet friendly

from $272 / night

1 / 19

Edisto Island House

  • 4
  • 10
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Ask about pets

from $133 / night

1 / 19

Edisto Island House

  • 4
  • 8
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Ask about pets

from $108 / night

1 / 20

Edisto Island House

  • 4
  • 10
  • 3 nights min
  • Swimming pool
  • Child friendly
  • Air conditioning

from $216 / night

(1)

1 / 20

Edisto Island House

  • 4
  • 12
  • 3 nights min
  • Child friendly
  • Ask about pets

$141

Excellent (1 reviews)

Inquire

from $141 / night

1 / 17

Edisto Island House

  • 4
  • 11
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Pet friendly

from $308 / night

1 / 18

Edisto Island House

  • 4
  • 12
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Ask about pets

from $185 / night

1 / 22

Edisto Island House

  • 4
  • 10
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Ask about pets

from $216 / night

1 / 16

Edisto Island House

  • 4
  • 10
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Ask about pets

from $183 / night

1 / 19

Edisto Island House

  • 4
  • 10
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Ask about pets

from $183 / night

1 / 21

Edisto Island House

  • 4
  • 11
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Ask about pets

from $265 / night

(1)

1 / 20

Edisto Island House

  • 4
  • 10
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Pet friendly

$163

Very Good (1 reviews)

Inquire

from $163 / night

1 / 20

Edisto Island House

  • 4
  • 8
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Ask about pets

from $125 / night

1 / 17

Edisto Island House

  • 4
  • 10
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Ask about pets

from $116 / night

1 / 38

Edisto Island House

  • 4
  • 11
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Pet friendly

from $125 / night

1 / 19

Edisto Island House

  • 4
  • 9
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Ask about pets

from $165 / night

1 / 20

Edisto Island House

  • 4
  • 12
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Ask about pets

from $249 / night

1 / 12

Edisto Island House

  • 4
  • 8
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Ask about pets

from $300 / night

(4)

1 / 20

Edisto Island House

  • 4
  • 10
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Ask about pets

$200

Average (4 reviews)

Inquire

from $200 / night

1 / 19

Edisto Island House

  • 4
  • 12
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Ask about pets

from $216 / night

1 / 19

Edisto Island House

  • 4
  • 9
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Pet friendly

from $141 / night

(2)

1 / 15

Edisto Island House

  • 4
  • 8
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Ask about pets

$120

Very Good (2 reviews)

Inquire

from $120 / night

1 / 32

Edisto Island House

  • 4
  • 12
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Ask about pets

from $451 / night

(1)

1 / 22

Edisto Island House

  • 4
  • 11
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Ask about pets

$272

Excellent (1 reviews)

Inquire

from $272 / night

1 / 19

Edisto Island House

  • 4
  • 9
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Pet friendly

from $115 / night

1 / 10

Edisto Island House

  • 4
  • 10
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Pet friendly

from $125 / night

(1)

1 / 15

Edisto Island House

  • 4
  • 10
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Pet friendly

$157

Excellent (1 reviews)

Inquire

from $157 / night