Search 105,200+ Vacation Rentals

Edisto Island 4+ bedroom Beach Rentals, Vacation Rentals & More - 190 Rentals Available.

Payment Protection
To book this vacation rental you need to pay through the Vacation Home Rentals website. We can’t protect your payment if you don’t pay through us. Learn more

190 Vacation rentals

Filters applied: 4+ Bedrooms

1 / 41

Edisto Island House

  • 5
  • 14
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Ask about pets

from $328 / night

1 / 34

Edisto Island House

  • 4
  • 12
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Ask about pets

from $141 / night

1 / 20

Edisto Island House

  • 4
  • 12
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Ask about pets

from $247 / night

1 / 12

Edisto Island House

  • 4
  • 10
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Ask about pets

from $208 / night

1 / 22

Edisto Island House

  • 5
  • 10
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Pet friendly

from $399 / night

(1)

1 / 18

Edisto Island House

  • 4
  • 9
  • 3 nights min
  • Swimming pool
  • Child friendly
  • Air conditioning

$149

Excellent (1 reviews)

Inquire

from $149 / night

(1)

1 / 43

Edisto Island House

  • 4
  • 16
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Ask about pets

$237

Very Good (1 reviews)

Inquire

from $237 / night

1 / 19

Edisto Island House

  • 4
  • 8
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Ask about pets

from $114 / night

(1)

1 / 19

Edisto Island House

  • 4
  • 9
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Pet friendly

$149

Excellent (1 reviews)

Inquire

from $149 / night

1 / 22

Edisto Island House

  • 6
  • 14
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Ask about pets

from $532 / night

(2)

1 / 22

Edisto Island House

  • 5
  • 12
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Ask about pets

$366

Very Good (2 reviews)

Inquire

from $366 / night

1 / 12

Edisto Island House

  • 4
  • 8
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Ask about pets

from $299 / night

1 / 19

Edisto Island House

  • 4
  • 8
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Pet friendly

from $158 / night

1 / 22

Edisto Island House

  • 4
  • 10
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Ask about pets

from $215 / night

1 / 18

Edisto Island House

  • 4
  • 10
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Pet friendly

from $274 / night

(1)

1 / 26

Edisto Island House

  • 5
  • 11
  • 3 nights min
  • Swimming pool
  • Child friendly
  • Air conditioning

$185

Excellent (1 reviews)

Inquire

from $185 / night

1 / 19

Edisto Island House

  • 4
  • 10
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Pet friendly

from $185 / night

1 / 13

Edisto Island House

  • 4
  • 8
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Ask about pets

from $158 / night

1 / 22

Edisto Island House

  • 4
  • 10
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Pet friendly

from $179 / night

1 / 15

Edisto Island House

  • 4
  • 8
  • 3 nights min
  • Swimming pool
  • Child friendly
  • Air conditioning

from $222 / night

1 / 22

Edisto Island House

  • 5
  • 11
  • 3 nights min
  • Swimming pool
  • Child friendly
  • Air conditioning

from $300 / night

1 / 19

Edisto Island House

  • 4
  • 12
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Ask about pets

from $249 / night

1 / 19

Edisto Island House

  • 4
  • 12
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Ask about pets

from $215 / night

1 / 20

Edisto Island House

  • 8
  • 16
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Ask about pets

from $333 / night

1 / 22

Edisto Island House

  • 4
  • 8
  • 3 nights min
  • Child friendly
  • Pet friendly

from $141 / night

(1)

1 / 40

Edisto Island House

  • 6
  • 14
  • 3 nights min
  • Swimming pool
  • Child friendly
  • Air conditioning

$465

Excellent (1 reviews)

Inquire

from $465 / night

1 / 22

Edisto Island House

  • 4
  • 12
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Pet friendly

from $250 / night

1 / 19

Edisto Island House

  • 4
  • 10
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Ask about pets

from $133 / night

(3)

1 / 21

Edisto Island House

  • 5
  • 11
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Ask about pets

$258

Excellent (3 reviews)

Inquire

from $258 / night

1 / 41

Edisto Island House

  • 6
  • 16
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Pet friendly

from $249 / night

1 / 31

Edisto Island House

  • 4
  • 14
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Ask about pets

from $115 / night

(1)

1 / 29

Edisto Island House

  • 7
  • 18
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Ask about pets

$550

Excellent (1 reviews)

Inquire

from $550 / night

1 / 20

Edisto Island House

  • 4
  • 11
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Ask about pets

from $157 / night

1 / 22

Edisto Island House

  • 4
  • 10
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Pet friendly

from $215 / night

1 / 24

Edisto Island House

  • 4
  • 12
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Ask about pets

from $357 / night

(1)

1 / 21

Edisto Island House

  • 6
  • 14
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Ask about pets

$500

Excellent (1 reviews)

Inquire

from $500 / night

(2)

1 / 20

Edisto Island House

  • 4
  • 14
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Ask about pets

$285

Very Good (2 reviews)

Inquire

from $285 / night

1 / 22

Edisto Island House

  • 4
  • 12
  • 3 nights min
  • Swimming pool
  • Child friendly
  • Air conditioning

from $465 / night

1 / 22

Edisto Island House

  • 6
  • 14
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Ask about pets

from $249 / night

1 / 16

Edisto Island House

  • 4
  • 12
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Ask about pets

from $141 / night