Search 105,200+ Vacation Rentals

Seabrook Island 4+ bedroom Vacation Rentals, House Rentals & More - 40 Rentals Available.

Payment Protection
To book this vacation rental you need to pay through the Vacation Home Rentals website. We can’t protect your payment if you don’t pay through us. Learn more

3 Vacation rentals

Filters applied: 4 Bedrooms

(24)

1 / 22

Seabrook Island House

  • 4
  • 10
  • Min stay varies
  • Ask about children
  • Air conditioning
  • Pet friendly

$265

Very Good (24 reviews)

Inquire

from $265 / night

(1)

1 / 24

Seabrook Island Townhouse

  • 4
  • 8
  • Min stay varies
  • Beach/lakeside relaxation
  • Child friendly
  • Air conditioning

$495

Excellent (1 reviews)

Book

from $495 / night

(2)

1 / 38

Seabrook Island House

  • 5
  • 11
  • Min stay varies
  • Beach/lakeside relaxation
  • Ask about children
  • Air conditioning

$400

Very Good (2 reviews)

Inquire

from $400 / night

Your search has been expanded 15.6 miles to include more rentals

1 / 33

Kiawah Island House - 8.5 miles away

  • 4
  • 10
  • 7 nights min
  • Beach/lakeside relaxation
  • Ask about children
  • Air conditioning

$2101

Inquire

from $2101 / night

1 / 30

Johns Island House - 8.5 miles away

  • 5
  • 10
  • Min stay varies
  • Ask about children
  • Air conditioning

from $551 / night

1 / 30

Johns Island House - 8.7 miles away

  • 4
  • 8
  • Min stay varies
  • Ask about children
  • Air conditioning

from $351 / night

1 / 18

Kiawah Island House - 8.8 miles away

  • 4
  • 10
  • Min stay varies
  • Ask about children
  • Air conditioning
  • Pet friendly

from $300 / night

1 / 29

Johns Island House - 12.2 miles away

  • 4
  • 12
  • Min stay varies
  • Swimming pool
  • Ask about children
  • Air conditioning

from $351 / night

1 / 30

Kiawah Island House - 12.3 miles away

  • 5
  • 12
  • Min stay varies
  • Swimming pool
  • Ask about children
  • Air conditioning

from $400 / night

(2)

1 / 22

Edisto Island House - 14.6 miles away

  • 4
  • 12
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Pet friendly

$191

Very Good (2 reviews)

Inquire

from $191 / night

1 / 21

Edisto Island House - 14.6 miles away

  • 4
  • 8
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Pet friendly

from $265 / night

(4)

1 / 20

Edisto Island House - 14.6 miles away

  • 4
  • 10
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Ask about pets

$200

Average (4 reviews)

Inquire

from $200 / night

1 / 22

Edisto Island House - 14.6 miles away

  • 4
  • 10
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Pet friendly

from $179 / night

(1)

1 / 17

Edisto Island House - 14.6 miles away

  • 4
  • 12
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Pet friendly

$249

Excellent (1 reviews)

Inquire

from $249 / night

1 / 34

Edisto Island House - 14.7 miles away

  • 4
  • 12
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Ask about pets

from $142 / night

(1)

1 / 32

Edisto Island House - 14.7 miles away

  • 4
  • 8
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Ask about pets

$216

Very Good (1 reviews)

Inquire

from $216 / night

1 / 19

Edisto Island House - 14.7 miles away

  • 4
  • 11
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Ask about pets

from $142 / night

(5)

1 / 18

Edisto Island House - 14.8 miles away

  • 4
  • 12
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Pet friendly

$337

Excellent (5 reviews)

Inquire

from $337 / night

1 / 35

Edisto Island House - 14.8 miles away

  • 4
  • 10
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Pet friendly

from $242 / night

1 / 22

Edisto Island House - 14.9 miles away

  • 5
  • 14
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Pet friendly

from $286 / night

(1)

1 / 21

Edisto Island House - 14.9 miles away

  • 6
  • 12
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Ask about pets

$371

Very Good (1 reviews)

Inquire

from $371 / night

1 / 20

Edisto Island House - 14.9 miles away

  • 4
  • 10
  • 3 nights min
  • Swimming pool
  • Child friendly
  • Air conditioning

from $216 / night

1 / 22

Edisto Island House - 14.9 miles away

  • 4
  • 8
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Pet friendly

from $271 / night

1 / 16

Edisto Island House - 14.9 miles away

  • 4
  • 12
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Ask about pets

from $133 / night

1 / 33

Edisto Island House - 14.9 miles away

  • 4
  • 12
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Pet friendly

from $165 / night

(1)

1 / 17

Edisto Island House - 15 miles away

  • 4
  • 12
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Ask about pets

$242

Very Good (1 reviews)

Inquire

from $242 / night

1 / 13

Edisto Island House - 15 miles away

  • 4
  • 10
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Ask about pets

from $150 / night

(1)

1 / 20

Edisto Island House - 15 miles away

  • 4
  • 12
  • 3 nights min
  • Child friendly
  • Ask about pets

$142

Excellent (1 reviews)

Inquire

from $142 / night

1 / 22

Edisto Island House - 15 miles away

  • 5
  • 10
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Pet friendly

from $283 / night

1 / 22

Edisto Island House - 15.1 miles away

  • 5
  • 12
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Ask about pets

from $326 / night

(3)

1 / 22

Edisto Island House - 15.2 miles away

  • 4
  • 8
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Pet friendly

$182

Very Good (3 reviews)

Inquire

from $182 / night

(1)

1 / 37

Edisto Island House - 15.2 miles away

  • 6
  • 16
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Ask about pets

$265

Average (1 reviews)

Inquire

from $265 / night

1 / 17

Edisto Island House - 15.3 miles away

  • 4
  • 11
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Pet friendly

from $308 / night

1 / 18

Edisto Island House - 15.3 miles away

  • 4
  • 10
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Pet friendly

from $274 / night

(1)

1 / 20

Edisto Island House - 15.3 miles away

  • 4
  • 10
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Pet friendly

$162

Very Good (1 reviews)

Inquire

from $162 / night

1 / 21

Edisto Island House - 15.5 miles away

  • 4
  • 10
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Ask about pets

from $176 / night

(2)

1 / 27

Edisto Island House - 15.5 miles away

  • 6
  • 14
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Pet friendly

$466

Average (2 reviews)

Inquire

from $466 / night

(4)

1 / 19

Edisto Island House - 15.5 miles away

  • 4
  • 10
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Pet friendly

$391

Average (4 reviews)

Inquire

from $391 / night

1 / 21

Edisto Island House - 15.5 miles away

  • 4
  • 12
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Ask about pets

from $150 / night

1 / 18

Edisto Island House - 15.6 miles away

  • 5
  • 12
  • 3 nights min
  • Child friendly
  • Air conditioning
  • Pet friendly

from $315 / night